El Ouazzani T, Mei N
Exp Brain Res. 1981;42(3-4):442-52. doi: 10.1007/BF00237509.
Vagal sensitivity to carbohydrates (mainly glucose) and to acids (hydrochloric and acetic acids) was studied in the gastro-duodenal region of anesthetized cats. Action potentials were recorded extracellularly from the nodose ganglion by means of glass microelectrodes. Receptors responding to glucose perfusion were found at this level as well as receptors stimulated by acid perfusion. It is shown that each type of receptor was activated by only one kind of stimulus (carbohydrates and acids, respectively). These receptors must thus be considered as true glucoreceptors or acido-receptors. Being silent before activation, these two types of chemoreceptors discharged at a frequency that varied from 2 to 14 imp/s for the acido-receptors, and from 2 to 30 imp/s for the glucoreceptors. The response could be irregular or regular and might last several minutes. Its latency was short (between 1 and 20 s for both types of chemoreceptors. It was therefore supposed that they were located in the mucosa or neighboring structures. From the conduction velocities (0.8-1.2 m/s), it was concluded that fibers originating from the acido- and glucoreceptors belonged to the C type. Recording of the electromyographic activity from the gastro-duodenal region demonstrated that the gluco- and acid-receptors are involved in the regulation of motility of the gastric and duodenal regions.
在麻醉猫的胃十二指肠区域研究了迷走神经对碳水化合物（主要是葡萄糖）和酸（盐酸和乙酸）的敏感性。通过玻璃微电极从结状神经节细胞外记录动作电位。在这个水平发现了对葡萄糖灌注有反应的感受器以及被酸灌注刺激的感受器。结果表明，每种类型的感受器仅由一种刺激（分别为碳水化合物和酸）激活。因此，这些感受器必须被视为真正的葡萄糖感受器或酸感受器。这两种化学感受器在激活前处于静息状态，激活后放电频率有所不同，酸感受器为2至14次冲动/秒，葡萄糖感受器为2至30次冲动/秒。反应可能不规则或规则，可能持续几分钟。其潜伏期较短（两种化学感受器均在1至20秒之间）。因此推测它们位于黏膜或邻近结构中。根据传导速度（0.8 - 1.2米/秒）得出结论，来自酸感受器和葡萄糖感受器的纤维属于C型。胃十二指肠区域肌电图活动的记录表明，葡萄糖感受器和酸感受器参与胃和十二指肠区域运动的调节。
