Müller-Wening W, Ruland F, Wenner J, von der Hardt H
Monatsschr Kinderheilkd (1902). 1978 Nov;126(11):667-71.
In 16 babies aged one month to 11 months, lung mechanics were studied before and after subcutaneous injection of a bronchodilator; in addition, total serum IgE and various Virus-Complement-Binding Reactions (CBR) were determined. All the babies showed the clinical signs of bronchial obstruction, but the total lung resistance and the dynamic lung compliance were not significantly altered after the injection. No relationship existed between the height of the serum IgE-value and the results of the Virus-CBR. It could not be confirmed that babies with wheezy bronchitis and a raised IgE-value reacted any better to the bronchodilator than babies with bronchial obstruction and a normal IgE-value.
对16名年龄在1个月至11个月的婴儿,在皮下注射支气管扩张剂前后研究了肺力学;此外,还测定了血清总IgE和各种病毒补体结合反应(CBR)。所有婴儿均表现出支气管阻塞的临床体征,但注射后总肺阻力和动态肺顺应性无明显改变。血清IgE值的高低与病毒补体结合反应的结果之间不存在相关性。无法证实喘息性支气管炎且IgE值升高的婴儿对支气管扩张剂的反应比支气管阻塞且IgE值正常的婴儿更好。