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[胎儿血液流变学特性的研究(作者译)]

[Studies on the rheological characteristics of fetal blood (author's transl)].

作者信息

Kaibara M, Marumoto Y, Kobayashi T

出版信息

Nihon Sanka Fujinka Gakkai Zasshi. 1980 Jul;32(7):873-8.

PMID:7240866
Abstract

Viscosity of fetal and adult blood was measured and compared. The viscosity was measured with a Contraves viscometer at a low shear rate of 0.535 sec(-1). There was no significant difference in the mean value of viscosity between fetal and adult blood. The viscosity of the adult blood showed the time dependent change when measured at the constant shear rate, but fetal one showed no such change. The mixture of adult plasma and fetal red blood cells (hematocrit: 50%) showed the same rheological characteristics as that of adult. On the contrary the mixture of fetal plasma and adult red blood cells showed the rheological characteristics of fetal blood. When the adult blood was observed under microscope numerous rouleaux of red blood cells were observed. However fetal blood showed numerous dispersed red blood cells and only a few poor rouleaux of red blood cells. It was suggested that the rheological characteristics of fetal blood was due to the fetal plasma which contained lower concentrations of fibrinogen and globulin, and which prevented the red blood cells aggregating to form rouleaux.

摘要

对胎儿血液和成人血液的粘度进行了测量和比较。使用Contraves粘度计在0.535秒-1的低剪切速率下测量粘度。胎儿血液和成人血液的粘度平均值没有显著差异。在恒定剪切速率下测量时,成人血液的粘度显示出随时间的变化,而胎儿血液则没有这种变化。成人血浆和胎儿红细胞(血细胞比容:50%)的混合物表现出与成人相同的流变学特性。相反,胎儿血浆和成人红细胞的混合物表现出胎儿血液的流变学特性。在显微镜下观察成人血液时,可观察到大量红细胞叠连。然而,胎儿血液显示出大量分散的红细胞,只有少数不良的红细胞叠连。有人提出,胎儿血液的流变学特性归因于胎儿血浆,其纤维蛋白原和球蛋白浓度较低,可防止红细胞聚集形成叠连。

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