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实验性动脉瘤:制作技术的改进

Experimental arterial aneurysms:modification of the production technique.

作者信息

O'Reilly G V, Utsunomiya R, Rumbaugh C L, Colucci V M

出版信息

J Microsurg. 1981 Mar;2(3):219-23. doi: 10.1002/micr.1920020311.

DOI:10.1002/micr.1920020311
PMID:7241046
Abstract

Vein pouches obtained from the external jugular vein were used to create experimental aneurysms on the carotid arteries of 13 rabbits and the abdominal aortas of 18 rabbits. Eighteen of these vein pouch aneurysms were grafted onto a linear incision in the artery; 13 of the aneurysms were grafted onto an elliptical incision. In 4 of the rabbits in which the vein pouch was grafted onto an elliptical arteriotomy in the carotid, a new approach for producing an intracranial aneurysm was attempted by relocating the aneurysm segment to the subarachnoid space at the cranial vertex. The results indicate that the aneurysms grafted onto an elliptical arteriotomy had a higher patency rate than the aneurysms grafted onto a linear arteriotomy in both the aortic and carotid models. Also, the attempt to produce an intracranial model demonstrated that short-term patency of the aneurysms could be achieved and that a two-stage approach to creating such aneurysms would be more appropriate than a one-stage approach.

摘要

从颈外静脉获取静脉囊,用于在13只兔子的颈动脉和18只兔子的腹主动脉上制造实验性动脉瘤。这些静脉囊动脉瘤中有18个被移植到动脉的线性切口上;13个动脉瘤被移植到椭圆形切口上。在4只将静脉囊移植到颈动脉椭圆形动脉切开处的兔子中,尝试了一种新的制造颅内动脉瘤的方法,即将动脉瘤段重新定位到颅顶的蛛网膜下腔。结果表明,在主动脉和颈动脉模型中,移植到椭圆形动脉切开处的动脉瘤的通畅率高于移植到线性动脉切开处的动脉瘤。此外,制造颅内模型的尝试表明,可以实现动脉瘤的短期通畅,并且两阶段制造此类动脉瘤的方法比一阶段方法更合适。

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Experimental arterial aneurysms:modification of the production technique.实验性动脉瘤:制作技术的改进
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Neurosurg Rev. 2023 Feb 14;46(1):56. doi: 10.1007/s10143-023-01953-1.
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Preclinical extracranial aneurysm models for the study and treatment of brain aneurysms: A systematic review.用于研究和治疗脑动脉瘤的临床前颅内动脉瘤模型:系统评价。
J Cereb Blood Flow Metab. 2020 May;40(5):922-938. doi: 10.1177/0271678X20908363. Epub 2020 Mar 3.
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Experimental saccular aneurysms. I. Review of surgically-constructed models and their laboratory applications.
实验性囊状动脉瘤。I. 手术构建模型及其实验室应用综述。
Neuroradiology. 1994 Oct;36(7):537-46. doi: 10.1007/BF00593517.