Hashimoto T
Aneurysm Research Laboratory, University of California, Santa Barbara.
Neurol Res. 1993 Jun;15(3):185-91. doi: 10.1080/01616412.1993.11740133.
An experimental study to measure the velocity profile within aneurysms has not been previously reported, although some theoretical works have been done. In the present studies, measurements of the velocity and pressure waveforms within model aneurysms have been done using a constant temperature hot film anemometer and a high frequency pulsed directional ultrasonic Doppler. A vein grafted aneurysm model was used in this investigation. Turbulent flow was detected at the neck and body of aneurysms. Pressure waveforms were compared between aneurysms and the parent vessel. The results suggest that turbulence evidenced by the distorted flow and high pressure pulse waves may plan an important role in the growth and rupture of a cerebral aneurysm. The mechanisms of the growth and rupture of a cerebral aneurysm are discussed.
尽管已经开展了一些理论研究工作,但此前尚未有关于测量动脉瘤内速度分布的实验研究报道。在本研究中,使用恒温热膜风速仪和高频脉冲定向超声多普勒仪对模型动脉瘤内的速度和压力波形进行了测量。本研究采用了静脉移植动脉瘤模型。在动脉瘤的颈部和主体部位检测到了湍流。比较了动脉瘤与母血管之间的压力波形。结果表明,由扭曲的血流和高压脉搏波所证明的湍流可能在脑动脉瘤的生长和破裂中起重要作用。文中还讨论了脑动脉瘤生长和破裂的机制。