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[鼠疫毒素暴露期间啮齿动物肝脏、心脏和骨骼肌中糖原水平的变化]

[Change in the glycogen level in the liver, heart and skeletal muscles of rodents during exposure to plague toxin].

作者信息

Kratinov A G, Khar'kova N M

出版信息

Vopr Med Khim. 1971 Jul-Aug;17(4):373-9.

PMID:5317618
Abstract

Three-hours intoxication induced by sublethal doses of autolysate or of fraction II of Pasteurella pestis EV in albino rats, guinea pigs and Meriones meridianus nogaiorum Heptn. resulted in a decrease of glycogen content in liver and calf muscles. In albino rats which are highly sensitive to plague toxin, this decrease was more significant compared to more resistant guinea pigs. Under the action of plague toxin on myocardium of Meriones and guinea pigs, glycogen content decreased while in albino rats increased. Plaque intoxication resulted in a statistically significant decrease of ascorbic acid concentration in adrenal gland and in liver in all rodent species studied.

摘要

用亚致死剂量的鼠疫耶尔森菌EV自溶物或组分II对白化大鼠、豚鼠和子午沙鼠进行三小时染毒后,肝和小腿肌肉中的糖原含量降低。对白喉毒素高度敏感的白化大鼠,与抗性更强的豚鼠相比,这种降低更为显著。在鼠疫毒素作用下,子午沙鼠和豚鼠心肌中的糖原含量降低,而白化大鼠的糖原含量增加。鼠疫染毒导致所有受试啮齿动物的肾上腺和肝脏中抗坏血酸浓度在统计学上显著降低。

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[Change in the glycogen level in the liver, heart and skeletal muscles of rodents during exposure to plague toxin].[鼠疫毒素暴露期间啮齿动物肝脏、心脏和骨骼肌中糖原水平的变化]
Vopr Med Khim. 1971 Jul-Aug;17(4):373-9.
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