Yaguchi S, Ogi M, Yamashina K, Kobayashi T, Takeuchi Y, Kagaya H, Matsushima T, Kitahama K
Jpn J Antibiot. 1980 Dec;33(12):1259-67.
Cefoxitin was administered to a total of 17 patients with intractable bronchopulmonary infections who had failed to respond to other conventional antibiotics, and the following results were obtained. (1) The clinical response, except 1 patient classified as evaluation impossible, was excellent in 3 patients, good in 10 and fair in 3 with an efficacy rate of 81.3%. (2) An improvement rate of more than 70% was observed in the findings of body temperature, dyspnea, colour of sputum, WBC and CRP. (3) There was no subjective nor objective side effects attributable to cefoxitin. In view of the results stated above, we have concluded that cefoxitin is a useful antibiotic for the treatment of intractable bronchopulmonary infections.
对17例难治性支气管肺部感染患者使用头孢西丁进行治疗，这些患者对其他常规抗生素治疗无效，获得了以下结果。（1）除1例无法评估外，临床反应为：3例优秀，10例良好，3例尚可，有效率为81.3%。（2）体温、呼吸困难、痰液颜色、白细胞和C反应蛋白等指标的改善率超过70%。（3）未观察到由头孢西丁引起的主观或客观副作用。鉴于上述结果，我们得出结论：头孢西丁是治疗难治性支气管肺部感染的有效抗生素。
