Gavron J P, Ardito J A, Curtis A W
Laryngoscope. 1981 Jul;91(7):1176-80. doi: 10.1288/00005537-198107000-00017.
Necrotizing sialometaplasia of salivary gland tissue is a benign, self-limiting disease usually confined to the minor salivary glands. To date only 49 cases have been reported. The clinical and histologic appearance may simulate squamous cell carcinoma, and unnecessary mutilating surgery may be performed if an erroneous diagnosis is made. The otolaryngologist must recognize this disease entity since it heals spontaneously and requires no treatment. Necrotizing sialometaplasia has no known premalignant potential.
涎腺组织坏死性涎腺化生是一种良性的、自限性疾病，通常局限于小涎腺。迄今为止，仅报道了49例。其临床和组织学表现可能类似鳞状细胞癌，如果诊断错误，可能会进行不必要的致残性手术。耳鼻喉科医生必须认识到这种疾病实体，因为它可自发愈合且无需治疗。坏死性涎腺化生没有已知的恶变潜能。
