Skinhøj P, Gluud C, Ramsøe K
Scand J Infect Dis. 1981;13(1):1-4. doi: 10.1080/00365548.1981.11690358.
This study concerns 105 patients with acute viral hepatitis, apparently contracted abroad. They comprised 27% of all cases of traveller's hepatitis notified in Denmark during 1976 to 1978. 88% were HBsAg-negative, probably type A hepatitis. 85% of the patients were aged 18-45 years. Two-thirds of all patients had been on individual journeys for more than 2 weeks, mainly in Africa or Southern Asia. Areas of risk for tourist group travellers (30 cases) were established to be Northern and Central Africa. The data support the present restricted use of immune serum globulin rather than general prophylaxis to all travellers.
本研究涉及105例急性病毒性肝炎患者,显然是在国外感染的。他们占1976年至1978年丹麦报告的所有旅行者肝炎病例的27%。88%的患者乙肝表面抗原阴性,可能为甲型肝炎。85%的患者年龄在18至45岁之间。所有患者中有三分之二进行了超过2周的个人旅行,主要在非洲或南亚。已确定旅游团旅行者(30例)的风险地区为北非和中非。这些数据支持目前对免疫血清球蛋白的有限使用,而不是对所有旅行者进行普遍预防。