Meyer F D, Häcki W, Beglinger C, Stalder G A, Gyr K
Schweiz Med Wochenschr. 1981 May 30;111(22):813-4.
In four healthy volunteers increasing doses of intravenous CCK-33 induced an increase in plasma PP concentration measured by RIA. PP concentration rose from a basal level of 67 +/- 15 pmol/l to 198 +/- 45 pmol/l with 2 IDU/kg/h (p less than 0.05). In four mongrel dogs equipped with Thomas cannulas, the same doses induced a more pronounced rise in plasma PP (p less than 0.01). It is concluded that intravenous CCK-33 induces the release of PP in man and dog in a dose-dependent manner.
在4名健康志愿者中，静脉注射递增剂量的CCK - 33可使通过放射免疫分析法测定的血浆胰多肽（PP）浓度升高。PP浓度从基础水平67±15 pmol/l升至198±45 pmol/l（2 IDU/kg/h）（p<0.05）。在4只配备托马斯套管的杂种犬中，相同剂量导致血浆PP更显著升高（p<0.01）。结论是静脉注射CCK - 33能以剂量依赖方式诱导人和犬释放PP。
