甲基汞和无机汞对神经生长因子诱导的鸡胚感觉神经节神经突生长的影响。
Effect of methylmercury and inorganic mercury on the nerve growth factor-induced neurite outgrowth in chick embryonic sensory ganglia.
作者信息
Nakada S, Saito H, Imura N
出版信息
Toxicol Lett. 1981 Apr;8(1-2):23-8. doi: 10.1016/0378-4274(81)90132-6.
PMID:7245237
Abstract
Methylmercury inhibited the fiber outgrowth in chick embryonic sensory ganglia in the presence of nerve growth factor (NGF) by 50% at 2 x 10(-6) M and completely depressed it at 5 x 10(-6) M. Whereas inorganic mercury completely inhibited the fiber outgrowth at 10(-4) M. The possible role of microtubules is discussed.
摘要
甲基汞在神经生长因子（NGF）存在的情况下，对鸡胚感觉神经节中的神经纤维生长具有抑制作用，在2×10⁻⁶M时抑制50%，在5×10⁻⁶M时则完全抑制。而无机汞在10⁻⁴M时完全抑制神经纤维生长。本文讨论了微管的可能作用。
Zotero 插件