Bogdanov A V, Galashina A G
Zh Vyssh Nerv Deiat Im I P Pavlova. 1981 Jan-Feb;31(1):121-8.
Multineuronal activity was studied in unrestrained cats with bundles of 7 electrodes (50 mcm dia of the tips) chronically implanted in the auditory and motor cortex. Impulses of the highest and lowest amplitude were isolated from each neurogram by an amplitude discriminator. By means of AI-128 analyser interval cross-histograms were built for spike series, isolated from two simultaneous records. Functional connections between neurones located under different electrodes at a distance of up to 500 mcm were defined by statistical dependence of spike series. A higher level of interneuronal interaction was revealed in the motor cortex. In both cortical zones, excitatory connections dominated for neurones which generated high amplitude spikes. For neurones with low amplitude spikes, connections of the inhibitory type were typical in the auditory cortex, and inhibitory and inhibitory-excitatory connections were typical for neurones in the motor cortex. The excitatory type of dependence in the auditory cortex was manifested on histograms during the first 6 ms after the triggering spike, in the motor cortex-by 4 to 6 ms more frequently; the inhibitory type was manifested in both zones only during the first 2 ms.
在未受约束的猫身上进行了多神经元活动的研究，将一束7根电极（尖端直径50微米）长期植入听觉和运动皮层。通过幅度鉴别器从每个神经图中分离出最高和最低幅度的脉冲。借助AI - 128分析仪，为从两个同步记录中分离出的尖峰序列构建间隔交叉直方图。通过尖峰序列的统计依赖性来确定位于不同电极下、距离达500微米的神经元之间的功能连接。在运动皮层中发现了更高水平的神经元间相互作用。在两个皮层区域中，对于产生高幅度尖峰的神经元，兴奋性连接占主导。对于低幅度尖峰的神经元，抑制性连接在听觉皮层中很典型，而在运动皮层中，抑制性和抑制 - 兴奋性连接对于神经元很典型。听觉皮层中兴奋性依赖类型在触发尖峰后的前6毫秒内在直方图上表现出来，在运动皮层中更频繁地在4至6毫秒时表现出来；抑制性类型仅在两个区域的前2毫秒内表现出来。
