Akaeda H, Nagai K, Okuda Y, Shinoto M, Okuda H
Acta Obstet Gynaecol Jpn. 1981 Jun;33(6):752-6.
In usual medical consultation, we have been met a lot of female patients suffering from disturbances of autonomic nervous system such as headache, shoulder-ache and so on. Experiments were designed to elucidate whether or not these disturbances of autonomic nervous system were induced by inflammation and accelerated by stimulant diets. Functions of autonomic nervous system were examined by lipolysis in rat epididymal adipose tissue which was partly controlled by sympathetic nervous system. It was found that free fatty acid release from the epididymal adipose tissue was considerably elevated by inflammation which was formed in abdominal wall or in abdominal cavity or oral administration of stimulant diets such as red pepper and white pepper, and that such elevation of lipolysis was significantly reduced by resection of the autonomic nerve. These results indicated that the inflammation and the stimulant diets induced excitement of sympathetic nerve which controlled the epididymal adipose tissue. Experiments were now in progress to clarify relationship between such excitement of sympathetic nervous system induced by the inflammation or by the stimulant diet and irregular complaints due to disturbances of autonomic nervous system.
在日常医疗咨询中，我们遇到了许多患有自主神经系统紊乱的女性患者，如头痛、肩痛等。设计实验以阐明这些自主神经系统紊乱是否由炎症引起并由刺激性饮食加速。通过大鼠附睾脂肪组织中的脂肪分解来检测自主神经系统的功能，该过程部分受交感神经系统控制。结果发现，腹壁、腹腔炎症或口服红辣椒和白胡椒等刺激性饮食所形成的炎症会使附睾脂肪组织中的游离脂肪酸释放显著升高，而这种脂肪分解的升高会因切除自主神经而显著降低。这些结果表明，炎症和刺激性饮食会引起控制附睾脂肪组织的交感神经兴奋。目前正在进行实验，以阐明由炎症或刺激性饮食引起的交感神经系统兴奋与自主神经系统紊乱导致的不规则症状之间的关系。
