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氯代烃类麻醉剂堕胎作用的实验研究(作者译)

[Experimental study on the abortive effects of chlorinated hydrocarbon anaesthetics (author's transl)].

作者信息

Kessler G, Schöntag G

出版信息

Prakt Anaesth. 1978 Jun;13(3):162-5.

PMID:724622
Abstract

The effects of inhalation anaesthetics derived from chlorinated hydrocarbons (halothane, ethrane, penthrane) on foetal development were studied in pregnant rats. Administration of the anaesthetics during the main organogenetic stage did not affect foetal development; but application during the embryonic stage resulted in increased incidence of intra-uterine deaths and difficult deliveries. No malformations were observed.

摘要

在怀孕大鼠中研究了源自氯代烃的吸入麻醉剂(氟烷、恩氟烷、戊氟烷)对胎儿发育的影响。在主要器官发生阶段给予麻醉剂不会影响胎儿发育;但在胚胎阶段给予麻醉剂会导致宫内死亡和难产的发生率增加。未观察到畸形。

相似文献

1
[Experimental study on the abortive effects of chlorinated hydrocarbon anaesthetics (author's transl)].氯代烃类麻醉剂堕胎作用的实验研究(作者译)
Prakt Anaesth. 1978 Jun;13(3):162-5.
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[The risks of chronic occupational exposure of pregnant operating theatre personnel to anaesthetic gases (author's transl)].怀孕手术室工作人员长期职业性接触麻醉气体的风险(作者译)
Z Prakt Anasth Wiederbeleb Intensivther. 1973 Oct;8(5):311-5.
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Eisei Shikenjo Hokoku. 1981;99:50-5.
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Dangers of chronic exposure to inhalation anaesthetics. Preventive measures.
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[The influence of ethrane on the electro- and pentylenetetrazol-convulsions in mice (author's transl)].[安氟醚对小鼠电惊厥和戊四氮惊厥的影响(作者译)]
Anaesthesist. 1975 Mar;24(3):118-9.
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[Toxicological studies on dichloromethane, a solvent simulating carbon monoxide poisoning (author's transl)].
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[Anaesthesiological technique for pregnant rabbit, with consideration of foetal condition (author's transl)].妊娠兔的麻醉技术,并考虑胎儿状况(作者译)
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引用本文的文献

1
Embryotoxic/teratogenic potential of halothane.氟烷的胚胎毒性/致畸潜力。
Int Arch Occup Environ Health. 1990;62(4):263-71. doi: 10.1007/BF00640832.