Kessler G, Schöntag G
Prakt Anaesth. 1978 Jun;13(3):162-5.
The effects of inhalation anaesthetics derived from chlorinated hydrocarbons (halothane, ethrane, penthrane) on foetal development were studied in pregnant rats. Administration of the anaesthetics during the main organogenetic stage did not affect foetal development; but application during the embryonic stage resulted in increased incidence of intra-uterine deaths and difficult deliveries. No malformations were observed.
在怀孕大鼠中研究了源自氯代烃的吸入麻醉剂(氟烷、恩氟烷、戊氟烷)对胎儿发育的影响。在主要器官发生阶段给予麻醉剂不会影响胎儿发育;但在胚胎阶段给予麻醉剂会导致宫内死亡和难产的发生率增加。未观察到畸形。