Suppr超能文献

急性肾衰竭的血液透析;技术与监测(作者译)

[Haemodialysis in acute renal failure; technique and surveillance (author's transl)].

作者信息

Köhler R, Lehmann C, Osswald M

出版信息

Prakt Anaesth. 1978 Jun;13(3):191-6.

PMID:724626
Abstract

Access to the blood stream for haemodialysis is generally via an arterio-venous shunt. Experience has shown that the introduction of two Shaldon catheters (with a modified Seldinger technique) into the upper caval system does not require special surgical knowledge and shortens and simplifies the preparations for haemodialysis in acute renal failure. As the catheters can easily be changed over guide wires, correction of obstructions and bacteriological examinations of the catheter tips do not present a problem. There were no complications. With this simplified access the acute stage of renal failure can be bridged for up to 6--8 weeks. The diameter of the catheters ensures an adequate flow of 150--200 ml/min. In vitro tests with a modified catheter (not yet available commercially) established 1. that the flow rate could be increased by 45 percent without altering the pressure of the return flow, and 2. that its use did not increase the rate of haemolysis. Incorrect placing of the catheters--the venous limb should be higher, i.e. nearer the heart, than the "arterial" catheter--may raise the re-circulating fraction by 6--18 percent. Since heparinization is necessary for haemodialysis but carries the grave risk of haemorrhages, espeically in the patients of an intensive care unit, it is essential to provide the means for estimating partial thromboplastin time at the bed side. This allows the heparin doses to be sufficiently reduced to obviate haemorrhage during and after haemodialysis.

摘要

血液透析进入血流通常通过动静脉分流。经验表明,采用改良的Seldinger技术将两根Shaldon导管插入上腔静脉系统并不需要特殊的外科知识,并且缩短并简化了急性肾衰竭患者血液透析的准备工作。由于导管可以很容易地通过导丝进行更换,因此导管堵塞的纠正以及导管尖端的细菌学检查都不成问题。没有出现并发症。通过这种简化的通路,肾衰竭的急性期可以维持长达6至8周。导管的直径确保了150至200毫升/分钟的充足血流量。使用一种改良导管(尚未商业化)进行的体外试验表明:1. 在不改变回流压力的情况下,流速可以提高45%;2. 使用该导管不会增加溶血率。导管放置不当——静脉端应比“动脉”导管更高,即更靠近心脏——可能会使再循环率提高6%至18%。由于血液透析必须进行肝素化,但存在严重的出血风险,尤其是在重症监护病房的患者中,因此必须提供在床边估计部分凝血活酶时间的方法。这可以充分减少肝素剂量,以避免血液透析期间及之后的出血。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验