Vogiatzis K V, Makley T A, Werling K
Ann Ophthalmol. 1981 Apr;13(4):433-5.
A case of an enucleated phthisical eye was examined pathologically and was diagnosed as uveitis, subretinal granuloma, detached retina, phthisis bulbi. Twenty years later a more detailed study of multiple sections with differential stains revealed the existence of yeast-like bodies morphologically compatible with Cryptococcus neoformans. Systemic involvement was not found in this case, and the patient died 17 years later from an unrelated disease of the cardiovascular system. However an autopsy was not performed. Indirect fluorescent antibody staining technique on unstained deparaffinized sections of the eye tissue was positive for C. neoformans.
对一例眼球摘除的痨瘵性眼球病例进行了病理检查，诊断为葡萄膜炎、视网膜下肉芽肿、视网膜脱离、眼球痨。二十年后，对多个切片进行更详细的鉴别染色研究发现存在形态上与新型隐球菌相符的酵母样体。该病例未发现全身受累情况，患者17年后死于心血管系统的 unrelated disease。然而未进行尸检。对眼组织未染色的脱蜡切片进行间接荧光抗体染色技术检测，结果显示新型隐球菌呈阳性。
