Udell I J, Ballen P H, Mir R, Perry H D
Ann Ophthalmol. 1981 Apr;13(4):471-5.
Six cases of subconjunctival tumor clinically compatible with the appearance of subconjunctival lymphoma were evaluated. Two of the patients, Cases 1 and 2, were under treatment with either prednisone or gold therapy for severe rheumatoid arthritis. Patient 3 manifested further evidence of systemic disease (auxillary lymph node). Of the remaining cases, patient 4 had no further evidence of systemic involvement, whereas patient 5 was suspected of having a gastrointestinal tumor. The last case, a patient known to have pulmonary lymphoma, presented with dry eye and multiple subconjunctival lymphomatous masses. Immune surface marker studies demonstrated a B-cell monoclonal subconjunctival lymphoma, suggestive of an improved survival when compared to null cell-type lesions. Immune surface marker studies offer a new commercially available method for classifying and prognosticating subconjunctival lymphomas.
对6例临床症状与结膜下淋巴瘤表现相符的结膜下肿瘤患者进行了评估。其中2例患者(病例1和病例2)正在接受泼尼松或金疗法治疗严重类风湿性关节炎。患者3有系统性疾病的进一步证据(腋窝淋巴结)。在其余病例中,患者4没有系统性受累的进一步证据,而患者5怀疑患有胃肠道肿瘤。最后1例患者已知患有肺淋巴瘤,表现为干眼症和多个结膜下淋巴瘤肿块。免疫表面标志物研究显示为B细胞单克隆结膜下淋巴瘤,提示与无细胞型病变相比生存期有所改善。免疫表面标志物研究为结膜下淋巴瘤的分类和预后评估提供了一种新的商用方法。