Rodríguez J N, Cañavate M, Amián A, Muñiz R, Prados D
Servicio de Hematología y Hemoterapia, Hospital General de Huelvc.
Rev Clin Esp. 1994 Oct;194(10):913-5.
Ocular adnexa are rarely involved in lymphomas. Four cases are reported of lymphoma involving the ocular adnexa. In two cases a previous systemic involvement existed or simultaneous to the ocular involvement; another patient had systemically a different histological pattern to that observed in the ocular region, and the fourth patient only had ocular region, and the fourth patient only had ocular symptoms; we therefore recorded two cases of primary ocular lymphoma. The lymphoma was located at the orbit in two cases and at the conjunctiva in the other two cases; the condition was bilateral in three cases. The most common symptom was exophtalmus; other major symptoms were diplopia and disturbances in ocular motility. The histological examination revealed three low grade lymphomas and one case of intermediate grade. Management of patients included radiotherapy and different chemotherapeutic regimens with a good response in all cases. A higher ocular relapse rate was observed in those patients with systemic involvement; in one primary case the condition resolved spontaneously. A review of the literature on clinical, diagnostic and therapeutic issues is made.
眼附属器很少发生淋巴瘤。本文报告了4例累及眼附属器的淋巴瘤。其中2例先前存在全身受累或与眼部受累同时发生；另1例患者全身的组织学模式与眼部观察到的不同，第4例患者仅出现眼部症状；因此，我们记录了2例原发性眼淋巴瘤。淋巴瘤2例位于眼眶，另2例位于结膜；3例为双侧病变。最常见的症状是眼球突出；其他主要症状是复视和眼球运动障碍。组织学检查显示3例为低级别淋巴瘤，1例为中级别淋巴瘤。患者的治疗包括放疗和不同的化疗方案，所有病例均有良好反应。全身受累的患者眼部复发率较高；1例原发性病例病情自发缓解。本文对临床、诊断和治疗问题的文献进行了综述。
