粘噻唑，一种干扰呼吸作用的新型抗生素。
Myxothiazol, a new antibiotic interfering with respiration.
作者信息
Thierbach G, Reichenbach H
出版信息
Antimicrob Agents Chemother. 1981 Apr;19(4):504-7. doi: 10.1128/AAC.19.4.504.
Abstract
Myxothiazol, a new antibiotic from the myxobacterium Myxococcus fulvus, inhibited the growth of many yeasts and fungi at concentrations between 0.01 and 3 micrograms/ml. It was generally inactive against bacteria. The inhibitory effect was cytostatic. With Candida albicans, Saccharomyces cerevisiae, and Mucor hiemalis, the growth inhibition was neutralized by glucose. Soon after being added to a cell suspension, the compound almost completely blocked oxygen consumption.
摘要
粘噻唑是一种来自粘细菌富黄粘球菌的新型抗生素，在浓度为0.01至3微克/毫升之间时可抑制多种酵母和真菌的生长。它通常对细菌无活性。其抑制作用是细胞生长抑制性的。对于白色念珠菌、酿酒酵母和冬生毛霉，葡萄糖可中和其生长抑制作用。该化合物添加到细胞悬液后不久，几乎完全阻断了氧气消耗。
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