Kasza P, Gyarmati L
Pharmazie. 1978 Aug;33(8):526-7.
A comparative study was done by the authors between the active substance release characteristic of lipophilic and hydrophilic oitment bases and their rheological parameters. There was stated a significant difference due to the matrix concentration the last being an essential factor in determining the effective surface area. The water solubility of matrix constituents is plaxing an important role in formation of the effective surface area.
作者对亲脂性和亲水性软膏基质的活性物质释放特性及其流变学参数进行了比较研究。结果表明，由于基质浓度存在显著差异，而基质浓度是决定有效表面积的一个重要因素。基质成分的水溶性在有效表面积的形成中起着重要作用。
