Lindgren L
Br J Anaesth. 1981 Jun;53(6):653-62. doi: 10.1093/bja/53.6.653.
E.c.g. changes were compared in 152 children undergoing adenoidectomy of adenotonsillectomy (T + A) under halothane or enflurane anaesthesia. Junctional rhythm occurred in 4-16% of the children in adenoidectomy groups and in 11-33% in T + A groups. Bundle branch block occurred in 4% of the children anaesthetized with halothane, but not with enflurane and was particularly common in association with thiopentone and T + A operations; one patient had bifocal ventricular tachycardia. QT interval was prolonged compared with control after thiopentone (P less than 0.001) and thiopentone and suxamethonium (P less than 0.02). QT interval was not changed after Althesin with or without suxamethonium. Mean preanaesthetic QT interval (+/- SEM) was significantly prolonged (492 +/- 22 ms; normal 440 ms) in children showing aberrant conduction with chaotic rhythm, but normal (438 +/- 5 ms) when bundle branch block or junctional rhythm was present during halothane anaesthesia. QT interval was prolonged significantly in enflurane but not in halothane anaesthesia.
对152名在氟烷或安氟醚麻醉下接受腺样体切除术或腺样体扁桃体切除术（T+A）的儿童的心电图变化进行了比较。腺样体切除术组中4%至16%的儿童出现交界性心律，T+A组中11%至33%的儿童出现交界性心律。4%接受氟烷麻醉的儿童出现束支传导阻滞，而接受安氟醚麻醉的儿童未出现，且在硫喷妥钠和T+A手术相关情况下尤为常见；1例患者出现双灶性室性心动过速。硫喷妥钠给药后（P<0.001）以及硫喷妥钠和琥珀酰胆碱给药后（P<0.02），QT间期与对照组相比延长。使用阿耳法沙龙（Althesin）无论是否合用琥珀酰胆碱，QT间期均无变化。在表现为节律紊乱的异常传导的儿童中，麻醉前平均QT间期（±标准误）显著延长（492±22毫秒；正常为440毫秒），但在氟烷麻醉期间出现束支传导阻滞或交界性心律时QT间期正常（438±5毫秒）。安氟醚麻醉时QT间期显著延长，而氟烷麻醉时未延长。
