Barber P C
Brain Res. 1981 Jul 20;216(2):239-51. doi: 10.1016/0006-8993(81)90127-x.
After surgical section of the vomeronasal nerves the neurosensory cells in the vomeronasal epithelium die. Electron microscopy has been used to demonstrate that their axons, and synaptic terminals in the accessory olfactory bulb degenerate and are removed by phagocytic astroglia. The vacated postsynaptic sites in the accessory bulb persist, and are not re-innervated, either by vomeronasal or olfactory axons, as long as 150 days post-operatively. However, new neurosensory cells which are produced in the vomeronasal epithelium after vomeronasal nerve section do form axons. Light and electron microscope autoradiography of axonally transported material has been used to show that some of these axons grow back into the cranial cavity and form glomeruli in the main olfactory bulb, in regions where it is damaged or de-afferented. The regenerated vomeronasal glomeruli contain synapses between vomeronasal nerve terminals and dendrites of main bulb neurons.
在切断犁鼻神经后，犁鼻上皮中的神经感觉细胞死亡。电子显微镜已被用于证明它们的轴突以及副嗅球中的突触终末会退化，并被吞噬性星形胶质细胞清除。术后长达150天，副嗅球中腾空的突触后位点持续存在，且未被犁鼻或嗅轴突重新支配。然而，犁鼻神经切断后在犁鼻上皮中产生的新神经感觉细胞确实会形成轴突。利用轴突运输物质的光镜和电镜放射自显影术已表明，其中一些轴突会重新长入颅腔，并在主嗅球受损或去传入的区域形成小球。再生的犁鼻小球包含犁鼻神经终末与主嗅球神经元树突之间的突触。
