在豚鼠中，维生素C对甲基胆蒽起助癌剂的作用。
Vitamin C acts as a cocarcinogen to methylcholanthrene in guinea-pigs.
作者信息
Banic S
出版信息
Cancer Lett. 1981 Jan;11(3):239-42. doi: 10.1016/0304-3835(81)90114-2.
PMID:7248928
Abstract
Large doses of vitamin C were found to promote the induction of sarcomas by methylcholanthrene. The tumours appeared earlier in the group of guinea-pigs treated with vitamin C after injection of methylcholanthrene than in the control group injected with methylcholanthrene. The treatment of guinea-pigs with vitamin C after induction of tumours thus did not inhibit the growth of tumours.
摘要
研究发现，大剂量的维生素C会促进甲基胆蒽诱发肉瘤。在用甲基胆蒽注射后的豚鼠组中，注射维生素C的那组豚鼠出现肿瘤的时间比仅注射甲基胆蒽的对照组要早。因此，在肿瘤诱发后用维生素C治疗豚鼠并不能抑制肿瘤的生长。
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