Román O, Camuzzi A L, Villalón E, Klenner C
Cardiology. 1981;67(4):230-43. doi: 10.1159/000173248.
A long-term training program was performed on 30 chronic hypertensive female patients, stages I-II, WHO criteria. The effect on blood pressure (BP) and other physiological parameters, as exercise BP, heart rate, physical working capacity, VO2max, double product, were studied. Four phases were outlined throughout the trial: (1) 3 months training at 70% of the maximal heart rate; (2) 3 months without training; (3) 1 year training at the same level as phase I, and (4) 12 or more months with increasing intensity training over 70% of the maximal heart rate. Serial ergometric work tests were performed every 3 months. We observed a close relationship between physical working capacity and VO2max increases with training intensity. Resting BP fell significantly with training (182/114-161/97 mm Hg; p less than 0.001) but increased again when training was discontinued (161/97-179/115 mm Hg; p less than 0.001). BP persisted low throughout the trial, but there was a tendency to a further but not significant decrease when training intensity was raised over 70% of the maximal heart rate. Both the submaximal and maximal exercise BP showed similar changes to those found in the resting BP throughout the trial. The submaximal heart rate and the double product (BP X heart rate) also fell significantly with training but with maximal values not changing significantly throughout the whole follow-up period.
对30名符合世界卫生组织标准I-II期的慢性高血压女性患者实施了一项长期训练计划。研究了该计划对血压（BP）和其他生理参数的影响，如运动血压、心率、体力工作能力、最大摄氧量（VO2max）、双乘积。在整个试验过程中划分了四个阶段：（1）以最大心率的70%进行3个月训练；（2）3个月不训练；（3）以与第一阶段相同的水平进行1年训练；（4）12个月或更长时间进行强度超过最大心率70%的递增训练。每3个月进行一次系列测力计工作测试。我们观察到体力工作能力和最大摄氧量的增加与训练强度密切相关。静息血压随着训练显著下降（182/114 - 161/97毫米汞柱；p小于0.001），但在停止训练时再次升高（161/97 - 179/115毫米汞柱；p小于0.001）。在整个试验过程中血压持续较低，但当训练强度提高到超过最大心率的70%时，有进一步下降的趋势但不显著。在整个试验过程中，次极量和极量运动血压的变化与静息血压相似。次极量心率和双乘积（血压×心率）也随着训练显著下降，但在整个随访期间最大值没有显著变化。
