Franzini C, Lenzi P, Cianci T
Exp Brain Res. 1981;43(1):87-92. doi: 10.1007/BF00238813.
In our study we examined, in the rabbit, the interactions between temperature regulation and the state of increased vigilance and emotional arousal induced by a Classical Aversive Conditioning Procedure. A Delay Conditioning Procedure was used. The Conditioned Stimulus (CS) was a 1350 Hz, 85 dB tone, the Unconditioned Stimulus (UCS) a 1 mA, 0.5 s shock. Testing sessions were run at different ambient temperatures from 5 to 30 degrees C. At all ambient temperatures considered the CS induced desynchronisation of the EEG and stereotyped changes in all the autonomic variables studied. Hypothalamic temperature (Thy) first increased, then decreased below its initial value, whereas ear skin temperature (Ts) showed opposite changes. Respiratory frequency (RF) initially increased, then tended to revert to its original value. The average time course of this complex pattern was 300 s from the CS. The overall effect of the CS sequence in a session was a significant decrease in Thy and Ts and a significant increase in RF compared to control values at the beginning of the session. Both in the short (single trial) and long terms (whole session) the autonomic responses induced by the emotional stress (polypnoea and vasoconstriction) were not coherent from the point of view of thermoregulation. The hypothesis of an effect of emotional arousal in shifting set point temperatures can therefore be discarded in favour of a direct action of emotional stress on effector controllers for respiration and vasomotion.
在我们的研究中，我们在兔子身上研究了温度调节与经典厌恶条件反射程序所诱导的警觉性提高和情绪唤醒状态之间的相互作用。采用了延迟条件反射程序。条件刺激（CS）是1350赫兹、85分贝的音调，非条件刺激（UCS）是1毫安、0.5秒的电击。测试在5至30摄氏度的不同环境温度下进行。在所有考虑的环境温度下，CS均引起脑电图去同步化以及所研究的所有自主变量的刻板变化。下丘脑温度（Thy）先升高，然后降至初始值以下，而耳部皮肤温度（Ts）则呈现相反变化。呼吸频率（RF）最初升高，然后趋于恢复到其原始值。这种复杂模式的平均时间进程从CS开始起为300秒。与测试开始时的对照值相比，一次测试中CS序列的总体效应是Thy和Ts显著降低，RF显著升高。无论是短期（单次试验）还是长期（整个测试过程），从体温调节的角度来看，情绪应激所诱导的自主反应（呼吸急促和血管收缩）都不一致。因此，关于情绪唤醒在改变设定点温度方面起作用的假设可以被摒弃，而支持情绪应激对呼吸和血管运动效应器控制器的直接作用。
