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解剖学上位于希氏束的束支传导阻滞(作者译)

[The bundle branch block anatomically located in HIS bundle (author's transl)].

作者信息

Alboni P, Pedroni P, Malacarne C, Masoni A

出版信息

G Ital Cardiol. 1980;10(12):1583-7.

PMID:7250582
Abstract

Bundle branch block (BBB) patterns are commonly considered to represent conduction block in the corresponding bundle branch. However, several histological and experimental studies demonstrated the possibility of a BBB related to an anatomical lesion within the His bundle. Recently there has been demonstrated, also in clinical setting, the possibility of evaluation whether a left bundle branch block (LBBB) is related to an anatomical within such bundle. For this purpose the selective stimulation of the His bundle has been utilized. A distal simulation of such bundle (which can be evaluated by a stimulus-QRS interval shorter than HV interval) normalizing the QRS complexes compresses an anatomical lesion within the proximal His bundle. Such normalization cannot be attributed to a right septum stimulation since the LBBB pattern should be increased instead of disappearing. The Authors think that an anatomical localization within the His bundle can be evaluated only in LBBB. In fact it is possible that a right bundle branch block pattern, if a septal calcification or fibrosis is present, could be normalized also in the presence of an isoelectric line placed between the artificial stimulus and the QRS complex. There is criticized the concept supported by other Authors that normalization of the QRS complex may be related to a summation effect between the sinusal impulse and that artificially induced. In fact such effect can be easy excluded by analizing the temporal relationship between the ventriculograms registered during His bundle stimulation and the atriograms. The clinical implications of the LBBBs in relation with an anatomical lesion within the His bundle are discussed.

摘要

束支传导阻滞(BBB)模式通常被认为代表相应束支的传导阻滞。然而,一些组织学和实验研究表明,存在与希氏束内解剖学病变相关的束支传导阻滞的可能性。最近,在临床环境中也已证明,有可能评估左束支传导阻滞(LBBB)是否与该束支内的解剖学病变有关。为此,已采用希氏束的选择性刺激。对该束支进行远端刺激(可通过刺激-QRS间期短于HV间期来评估)使QRS波群正常化,提示近端希氏束内存在解剖学病变。这种正常化不能归因于右间隔刺激,因为LBBB模式应该增强而不是消失。作者认为,仅在LBBB中才能评估希氏束内的解剖学定位。事实上,如果存在间隔钙化或纤维化,即使在人工刺激和QRS波群之间存在等电位线,右束支传导阻滞模式也有可能正常化。本文批评了其他作者支持的观点,即QRS波群的正常化可能与窦性冲动和人工诱发冲动之间的总和效应有关。事实上,通过分析希氏束刺激期间记录的心室图与心房图之间的时间关系,可以很容易地排除这种效应。本文还讨论了与希氏束内解剖学病变相关的LBBB的临床意义。

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