Clain J E, Barbezat G O, Marks I N
Gut. 1981 May;22(5):355-8. doi: 10.1136/gut.22.5.355.
Calcium, enzyme, and total protein secretion were measured in secretin stimulated pancreatic juice in health, "early" chronic pancreatitis, and in chronic calcific pancreatitis. Increased concentrations of trypsin, total protein, and calcium, and increased outputs of calcium and protein were shown to be present in the "early" stages of the disease, indicating that an environment conducive to the formation of protein plugs and possibly later calcification already exists.
在健康人、“早期”慢性胰腺炎患者和慢性钙化性胰腺炎患者中,检测了促胰液素刺激的胰液中的钙、酶和总蛋白分泌情况。结果显示,在疾病的“早期”阶段,胰蛋白酶、总蛋白和钙的浓度升高,钙和蛋白的分泌量增加,这表明已经存在有利于蛋白质栓形成以及可能随后发生钙化的环境。