Möller G, König W
Immunology. 1981 Jun;43(2):255-60.
The binding parameters of chemically-defined immune complexes composed of rat IgGa-anti-human serum albumin (HSA) to rat basophilic leukaemia cells were analysed. It was demonstrated that the uptake of various sized immune complexes is time-, temperature- and pH-dependent. A higher binding rate was observed with more Fc portions available in the immune complex. A comparison of the binding rate for immune complexes with that of heat aggregates shows that immune complexes bind with greater affinity to the cells.
分析了由大鼠IgGa-抗人血清白蛋白(HSA)组成的化学定义免疫复合物与大鼠嗜碱性白血病细胞的结合参数。结果表明,不同大小免疫复合物的摄取具有时间、温度和pH依赖性。在免疫复合物中有更多可利用的Fc部分时,观察到更高的结合率。免疫复合物与热聚集体的结合率比较表明,免疫复合物与细胞的结合亲和力更高。