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实验性钩虫病期间小鼠的迟发型(细胞性)超敏反应。III. 过继免疫宿主中攻击幼虫固定潜伏期延长的影响。

Delayed (cellular) hypersensitivity in mice during experimental ancylostomiasis. III. Effect of longer latent period for immobilisation of challenged larvae in the adoptively immunized host.

作者信息

Vardhani V V, Johri G N

出版信息

J Hyg Epidemiol Microbiol Immunol. 1981;25(2):150-4.

PMID:7252144
Abstract

Sensitized and normal mesenteric lymph node cells were transferred separately into three groups of recipient female swiss albino mice. Recipients that received sensitized cells and challenged at 28 days after cell transfer produced rapid and early expulsion of larvae from the gastrointestinal tract and also destroyed them in muscles. Allergic immobilisation and death of the larvae may be due to the primary role of delayed type hypersensitivity response in this mouse model.

摘要

将致敏和正常的肠系膜淋巴结细胞分别转移到三组雌性瑞士白化小鼠受体中。接受致敏细胞并在细胞转移后28天受到攻击的受体,会迅速且早期地将幼虫从胃肠道排出,并在肌肉中破坏它们。幼虫的过敏性固定和死亡可能是由于该小鼠模型中迟发型超敏反应的主要作用。

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