Lal S, Garg B R, Hameedulla A
Lepr India. 1981 Apr;53(2):285-8.
Three out of 30 patients of leprosy getting clofazimine therapy developed severe gastrointestinal side effects following the therapy in the dose of 100 mg after one month, eight months and five weeks respectively. One of the patients died due to the side effects. Indian patients appear to be more prone to severe gastrointestinal side effects of clofazimine and may develop the same after shorter duration of therapy with smaller doses of the drug.
30例接受氯法齐明治疗的麻风病患者中,分别在治疗1个月、8个月和5周后,有3例患者在服用100毫克剂量的药物后出现了严重的胃肠道副作用。其中1例患者因副作用死亡。印度患者似乎更容易出现氯法齐明严重的胃肠道副作用,且可能在使用较小剂量药物治疗较短时间后就会出现。