Dupont P, Fuss M, Corvilain J
Rev Rhum Mal Osteoartic. 1978 Jul-Sep;45(7-9):491-7.
On the basis of 100 cases of hypercalcemia, the authors attempt to elucidate the criteria of the etiologic diagnosis. Kidney lithiasis or nephrocalcinosis suggested a primary hyperparathyroidism (HPT I) or an intoxication due to vitamin D. X rays of the skeleton and quantitative histological exams of the bone were not useful in the diagnosis of HPT I. The level of parathormone in the plasma is the best parameter to be used in distinguishing HPT I from other diseases. In the absence of renal insufficiency or severe intestinal disorders, a phospharemia below 2.6 mg/100 ml, a chloremia above 103 m EG/l and bicarbonates below 25 m Eg/l indicate an HPT I or a paraneoplasic. A phosphoremia above 3.2 mg/100 ml runs counter to this diagnosis. The chloremia/phosphoremia ratio is not more helpful than the phosphoremia alone.
基于100例高钙血症病例，作者试图阐明病因诊断标准。肾结石或肾钙质沉着提示原发性甲状旁腺功能亢进（I型甲状旁腺功能亢进症）或维生素D中毒。骨骼X线检查和骨定量组织学检查对I型甲状旁腺功能亢进症的诊断无用。血浆甲状旁腺激素水平是用于鉴别I型甲状旁腺功能亢进症与其他疾病的最佳参数。在没有肾功能不全或严重肠道疾病的情况下，血磷低于2.6mg/100ml、血氯高于103mEq/l且碳酸氢盐低于25mEq/l提示I型甲状旁腺功能亢进症或副肿瘤综合征。血磷高于3.2mg/100ml与该诊断不符。血氯/血磷比值并不比单独的血磷更有帮助。
