通过化学和酶促反应相结合的方法简便地合成嘌呤2'-氨基-2'-脱氧核糖苷。
A new and facile synthesis of purine 2'-amino-2'-deoxyribosides by a combination of chemical and enzymatic reactions.
作者信息
Morisawa H, Utagawa T, Nakamatsu T, Yamanaka S, Yamazaki A
出版信息
Nucleic Acids Symp Ser. 1980(8):s11-4.
PMID:7255182
Abstract
An enzymatic synthesis of 2'-amino-2'-deoxy-2-chloroinosine and its chemical conversion to purine 2'-amino-2'-deoxyribosides are described. In addition, some of 2'-amino-2'-deoxy-ribosides of 6-substituted purine were also prepared from 2'-amino-2'-deoxyinosine.
摘要
描述了2'-氨基-2'-脱氧-2-氯肌苷的酶促合成及其化学转化为嘌呤2'-氨基-2'-脱氧核糖苷的过程。此外，还从2'-氨基-2'-脱氧肌苷制备了一些6-取代嘌呤的2'-氨基-2'-脱氧核糖苷。
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