Berceanu-Gabrielescu A, Mănciulescu D, Marinescu I, Popovici D, Dinulescu E, Juvină E, Ioaniţiu D, Tache A, Cristoveanu A, Ciocirdia C, Bunea M, Sooliuc E, Panaitiu G, Augustin M
Endocrinologie. 1981 Apr-Jun;19(2):123-7.
The present work has attempted an analysis of the role hypercorticism as a risk factor in arterial hypertension and atherosclerosis. Our series consisted of 149 male and female patients of various ages. The incidence of cardiovascular disorders in relation to age and the glucidic lipidic metabolic disorders were also investigated. The results showed that hypercorticism may trigger in very young patients as well arterial hypertension (AH) and glucidic-lipid metabolic disorders both incriminated as risk factors in including atherosclerosis. Hypercorticism was proved to be an aggravating factor of pre-existing cardiopathy. Efficient management of adrenocortical hormones excess brings complete resolution of arterial hypertension and glucidic lipid metabolic disorders in young patients and most adult patients who had no cardiovascular complaints prior to the endocrine syndrome.
本研究试图分析皮质醇增多症作为动脉高血压和动脉粥样硬化风险因素的作用。我们的研究系列包括149名不同年龄段的男性和女性患者。还研究了心血管疾病的发病率与年龄以及糖脂代谢紊乱之间的关系。结果表明，皮质醇增多症可能在非常年轻的患者中引发动脉高血压（AH）和糖脂代谢紊乱，这两者均被认为是包括动脉粥样硬化在内的风险因素。皮质醇增多症被证明是已有心脏病的加重因素。有效管理肾上腺皮质激素过多可使年轻患者以及大多数在内分泌综合征之前没有心血管疾病主诉的成年患者的动脉高血压和糖脂代谢紊乱完全缓解。
