Nanu L, Petrescu R, Dinulescu E, Bartoc R, Ion V
Endocrinologie. 1981 Apr-Jun;19(2):97-103.
The effects of adrenaline alone or associated with Crinofizin, a pineal polypeptide extract, were studied on rats. The drug given 15 minutes before a hyperglycemic adrenaline dose counteracted the pharmacologic effects with lethal consequences of catecholamine as well as certain metabolic effects such as elevation of blood levels of glycerol, phospholipids and cholesterol. Post-adrenaline hyperglycemia was not reduced by Crinofizin under the given experimental circumstances. The glycogenolytic effect of adrenaline was slightly inhibited.
研究了单独使用肾上腺素或与松果体多肽提取物Crinofizin联合使用对大鼠的影响。在给予高血糖剂量肾上腺素前15分钟给予该药物，可抵消儿茶酚胺的药理作用及其致命后果，以及某些代谢作用，如甘油、磷脂和胆固醇血水平升高。在给定的实验条件下，Crinofizin并未降低肾上腺素后的高血糖。肾上腺素的糖原分解作用略有抑制。
