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钾代谢的房室分析——⁴²K示踪动力学的数学建模

[Compartment analysis of potassium metabolism--mathematical modelling of 42-K tracer kinetics].

作者信息

Neumann J, Wüstenberg P W, Esther G

出版信息

Z Gesamte Inn Med. 1981 Mar 15;36(6):273-4 suppl.

PMID:7257461
Abstract

The possibility of application of the theoretical concept of the compartment analysis in the modelling of the potassium balance was demonstrated. A use of the compartment analysis of the potassium balance in the clinical routine diagnostics in the sense of a highly specialised functional diagnostics seems according to recent experiences reasonable only in closest cooperation with clinicians. The diagnostics and the control of therapy of the chronic syndrome of potassium deficit as well as metabolically conditioned disturbances of the distribution of potassium were to be seen as possible indication. At the same time the establishment of reference values for the demarcation of relative disturbances of distribution as well as for the establishment of the normal region of the turnover rates were necessary.

摘要

已证明在钾平衡建模中应用隔室分析这一理论概念的可能性。根据最近的经验,仅在与临床医生密切合作的情况下,将钾平衡的隔室分析用于临床常规诊断(从高度专业化的功能诊断意义上来说)似乎才是合理的。钾缺乏慢性综合征的诊断和治疗控制以及钾分布的代谢性调节紊乱可被视为可能的适应症。同时,有必要建立用于划分相对分布紊乱的参考值以及用于确定周转率正常范围的参考值。

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