一种用于检验双基因座遗传模型的简单方法。
A simple method for testing two-locus models of inheritance.
作者信息
Greenberg D A
出版信息
Am J Hum Genet. 1981 Jul;33(4):519-30.
Abstract
A graphic method for testing simple two-locus models of inheritance is developed. The model assumes two alleles at each locus where both loci exhibit dominant, both exhibit recessive, or one locus exhibits dominant and one locus exhibits recessive inheritance. Examples of applying the graphs using published data on three diseases are given.
摘要
开发了一种用于测试简单双基因座遗传模型的图形方法。该模型假设每个基因座有两个等位基因，其中两个基因座均表现为显性、均表现为隐性，或者一个基因座表现为显性而另一个基因座表现为隐性遗传。给出了使用三种疾病的已发表数据应用这些图形的示例。
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