Ruebush T K, Piesman J, Collins W E, Spielman A, Warren M
Am J Trop Med Hyg. 1981 May;30(3):555-9. doi: 10.4269/ajtmh.1981.30.555.
To determine whether Ixodes dammini is capable of transmitting Babesia microti to primates, infected nymphal ticks were allowed to feed on five Macaca mulatta. The monkeys were then followed for at least 60 days with daily thick blood smears for evidence of infection. Patent B. microti parasitemia developed in four of the five animals. Prepatent periods were 13, 18, 20, and 28 days. Maximum parasitemia ranged from 83 to 7,068 organisms/mm3 blood. Splenectomy 15-17 months after exposure to ticks results in recurrences of parasitemia in three of the four infected monkeys.
为了确定达氏硬蜱是否能够将微小巴贝斯虫传播给灵长类动物,让受感染的若蜱叮咬5只猕猴。随后对这些猴子进行了至少60天的跟踪观察,每天制作厚血涂片以寻找感染证据。5只动物中有4只出现了微小巴贝斯虫显性虫血症。潜伏期分别为13、18、20和28天。最高虫血症水平为每立方毫米血液中有83至7068个虫体。在接触蜱虫15 - 17个月后进行脾切除,4只受感染的猴子中有3只出现了虫血症复发。