Gressier M, Estanove S, du Gres B, Brule P, Champsaur G
Anesth Analg (Paris). 1981;38(3-4):101-4.
Heart rate, cardiac index measured by thermodilution, systolic diastolic and mean arterial pressure, mean left and right atrial pressures, were measured immediately before and after 30 minutes of dopamine infusion at a rate of 7 micrograms/kg/minute, then after 30 minutes of nitroprusside infusion at a rate of 0.5 micrograms/kg/minute, and after 30 minutes of association dopamine-nitroprusside at the same doses. The statistical analysis shows that the best enhancement in the cardiac output is observed (P less than 0.01) after the association dopamine-nitroprusside, with a diminution of systemic vascular resistance (P less than 0.05) however less important than that observed with sodium nitroprusside alone (P less than 0.025).
在以7微克/千克/分钟的速率输注多巴胺30分钟之前和之后、然后以0.5微克/千克/分钟的速率输注硝普钠30分钟之后、以及以相同剂量联合输注多巴胺和硝普钠30分钟之后，测量心率、通过热稀释法测量的心指数、收缩压、舒张压和平均动脉压、左心房和右心房平均压。统计分析表明，联合输注多巴胺和硝普钠后观察到心输出量有最佳增强（P<0.01），全身血管阻力降低（P<0.05），但不如单独使用硝普钠时明显（P<0.025）。
