Graftieaux J P, Pozzo di Borgo C, Scherpereel B, Rousseaux P, Martinet J F, Aribert E, Bertault R, Rendoing J
Anesth Analg (Paris). 1981;38(3-4):113-7.
The authors have performed 66 (cranial or spinal) operations with electro-anaesthesia supplemented by neuroleptics and pancuronium. In this technique, which respects the necessities of neurosurgical anaesthesia, analgesia is produced by means of Limoge's rectified high frequency currents. The protocol consists of: induction by a neuroleptic, application of the electrical current, intubation with benzodiazepin and succicurarium, controlled ventilation with a 50 p. cent oxygen/50 p. cent nitrous oxyd mixture and curare as required. The efficiency was estimated according to the necessity of a supplementary drug analgesia (fentanyl). The use of fentanyl, i.e. drug intoxication, was strongly reduced in 90 p. cent of the cases (average 0,46 micrograms/kg/hour). Absolute failures were encountered in 3 cases only. Patients waked up in very good conditions and extubation occurred on an average of 16 minutes. Reflexes of cough an deglutition are not depressed by electro-anaesthesia and we think this preservation of the respiratory function to be very profitable for such neurosurgical patients. Our opinion by now is that the best indications for electro-anaesthesia are high-risk patients, with a special mention for surgery of the posterior fossa.
作者采用电麻醉并辅以神经安定药和潘库溴铵进行了66例（颅脑或脊柱）手术。在这种符合神经外科麻醉要求的技术中，通过利摩日整流高频电流产生镇痛效果。方案包括：用神经安定药诱导，施加电流，用苯二氮䓬和琥珀酰胆碱插管，用50%氧气/50%氧化亚氮混合气体按需进行控制通气并使用箭毒。根据是否需要追加药物镇痛（芬太尼）来评估疗效。在90%的病例中，芬太尼的使用即药物中毒情况大幅减少（平均0.46微克/千克/小时）。仅3例出现绝对失败。患者苏醒状态良好，平均16分钟后拔管。电麻醉不会抑制咳嗽和吞咽反射，我们认为这种对呼吸功能的保留对这类神经外科患者非常有益。我们目前的观点是，电麻醉的最佳适应证是高危患者，后颅窝手术尤其适用。
