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用¹²⁵I标记的蛋白A检测血小板抗体。

Detection of thrombocyte antibodies by 125I labeled protein A.

作者信息

Bergh O J, Solheim B G

出版信息

Tissue Antigens. 1978 Sep;12(3):189-94. doi: 10.1111/j.1399-0039.1978.tb01321.x.

Abstract

Protein A from Staphylococcus aureus interacts in a specific manner with most subclasses of human IgG. In the present study a method is described which utilizes Protein A labeled with 125I for the detection of antibody sensitization of platelets. The clinical applicability of the test for detection of in vivo or in vitro sensitization is demonstrated in three patients with platelet antibodies.

摘要

金黄色葡萄球菌的蛋白A与人类IgG的大多数亚类以特定方式相互作用。在本研究中,描述了一种利用用125I标记的蛋白A来检测血小板抗体致敏的方法。在三名患有血小板抗体的患者中证明了该检测体内或体外致敏的临床适用性。

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