Iamshchikov N V
Arkh Anat Gistol Embriol. 1981 Mar;80(3):64-8.
Subcellular reaction of certain structural components in the chick embryo myocardium to a single dose of the alkylating cyclophosphamide compound has been studied electron microscopically. It has been stated that the muscle cell edema, desorganization of the intracellular organells, reactions of the lysosomal apparatus occur in the myocardium. Two types of the cardiac muscle cell edema are revealed: 1) without any disturbance in intracellular organells; 2) with their advanced desorganization. Cells in the capillary endothelium are affected simultaneously to the muscle cells of the myocardium. Regenerative processes result in normalization of ultramicroscopical structure of the muscle cells. The subcellular reaction of the embryonal myocardium is characterized by a rapid course of the destructive and regenerative processes.
利用电子显微镜研究了鸡胚心肌中某些结构成分对单剂量烷基化环磷酰胺化合物的亚细胞反应。研究表明，心肌中会出现肌肉细胞水肿、细胞内细胞器紊乱以及溶酶体装置反应。揭示了两种类型的心肌细胞水肿：1）细胞内细胞器无任何紊乱；2）细胞器严重紊乱。毛细血管内皮细胞与心肌细胞同时受到影响。再生过程导致肌肉细胞超微结构正常化。胚胎心肌的亚细胞反应以破坏和再生过程的快速进程为特征。
