[Subcellular changes in rat myocardium in nephrotoxic glomerulonephritis].

Disorganization of the mitochondria, myofibrillae, sarcolemma, intra- and intercellular edema, swelling and pyknosis of the endothelium, capillary obstruction by the blood elements, thickening of the basal membranes were revealed in the myocardium of rats with Mazugi nephritis. The maximum changes were observed on the 10--20th day after the onset of the reproduction of glomerulonephritis; the intracellular regenerative processes became intensified from the 20th day. There was a correlation in the dynamics of the subcellular histological and clinical manifestations of glomerulonephritis.