Il'in A S
Biofizika. 1981 May-Jun;26(3):492-7.
A mathematical model of electroosmotic homeostasis in mammalian cells is developed. The need for the transmembrane ionic heterogeneity follows the requirement of the system's stability under varying conditions. The quantitative stability criterion is proposed, useful for estimating the physiological state of cells in experiment. The membrane growth in the case of stable cell-units promotes the development of surface invaginations into the internal volume. An invasive metastatic growth suggests the loss of stability.
建立了哺乳动物细胞电渗稳态的数学模型。跨膜离子异质性的需求遵循系统在不同条件下稳定性的要求。提出了定量稳定性标准,有助于在实验中估计细胞的生理状态。在稳定细胞单元的情况下,膜生长促进表面向内凹陷进入内部体积的发展。侵袭性转移生长表明稳定性丧失。