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Thermodynamics of alpha-lactalbumin unfolding.

作者信息

Pfeil W

出版信息

Biophys Chem. 1981 Apr;13(2):181-6. doi: 10.1016/0301-4622(81)80017-8.

DOI:10.1016/0301-4622(81)80017-8
PMID:7260334
Abstract

Thermodynamic investigations of alpha-lactalbumin have been performed by isothermal calorimetric guanidine hydrochloride titrations as well as by scanning calorimetric measurements in the presence and absence of guanidine hydrochloride. Compared with lysozyme, alpha-lactalbumin is less stable, and its changes of enthalpy and heat capacity at unfolding are lower. Thermal unfolding of alpha lactalbumin can be described to the first approximation by the two-state transition model even in the presence of guanidine hydrochloride.

摘要

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