Bochkov N I, Saakov B A, Bardakhch'ian E A
Biull Eksp Biol Med. 1981 Apr;91(4):492-5.
The experimental data indicate that in the toxemic period of burn disease primarily affected is the filtering barrier, chiefly podocytes and the basal membrane. Proteinuria that frequently occurs in severe thermal injuries is first of all accounted for by alterations in the glomerular filter membrane. Moreover, proteinuria is aggravated to a certain measure by resorption deficiency of the canaliculi. Morphologically this deficiency appears as hyaline-drop or vacuolar degeneration.
实验数据表明，在烧伤疾病的毒血症期，主要受影响的是滤过屏障，主要是足细胞和基底膜。严重热损伤中经常出现的蛋白尿首先是由肾小球滤过膜的改变引起的。此外，肾小管重吸收功能不足在一定程度上加重了蛋白尿。从形态学上看，这种功能不足表现为玻璃样滴状或空泡样变性。
