Chernukh A M, Alekseev O V, Vasadze O G
Biull Eksp Biol Med. 1981 May;91(5):528-30.
Mast cells and vascular permeability were examined in experimental aseptic peritonitis induced by intraperitoneal injection of starch into rats. It was established that derangement of vascular permeability in the inflammatory focus was consequent on degranulation of mast cells and release of inflammatory mediators. The model of the inflammation suggested enables the local focus to be created, with no mast cells seen for a long period of time (at least for 3 weeks).
通过向大鼠腹腔注射淀粉诱导实验性无菌性腹膜炎,检测肥大细胞和血管通透性。结果表明,炎症灶血管通透性的紊乱是肥大细胞脱颗粒和炎症介质释放的结果。所提出的炎症模型能够形成局部病灶,在很长一段时间内(至少3周)未见肥大细胞。