[Morphological and functional status of mast cells in the late stage of acute infectious inflammation].

The model of acute E. coli-induced infectious peritonitis in rats has been used to show that the late reparative stage of acute inflammation is followed by repopulation and regranulation of mast cells. The number of mast cells in the peritoneal fluid and mesrnterium vas resuscitated at the 90th day. At the same time regranulation of peritoneal mast cells was retarded in comparison with that of mast cells of the mesenterium and was not yet over by the 120th day. The increased degranulation of mast cells and free histamine content in the peritoneal fluid and mesenterium and histamine concentration in the blood testified to probable active role of mast cells in lste reparative events on the site of scute inflammation.