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[单层培养中胸腺和骨髓成纤维细胞集落上髓样细胞灶的形成]

[Formation of foci of myeloid cells on colonies of thymus and bone marrow fibroblasts in monolayer cultures].

作者信息

Kuznetsov S A, Luriia E A, Genkina E N

出版信息

Biull Eksp Biol Med. 1981 May;91(5):610-13.

PMID:7260394
Abstract

A culture system favouring myeloid cell formation directly on the surface of mouse stromal fibroblast colonies has been developed. It has been shown that the plaques formed are both much more numerous and essentially larger on stromal fibroblast colonies of thymus than of bone marrow origin. Consequently, hemopoietic precursor cells that form the myeloid plaques in the monolayer cultures interact dissimilarly with stromal mechanocytes of different origin.

摘要

已经开发出一种直接在小鼠基质成纤维细胞集落表面促进髓样细胞形成的培养系统。结果表明,在胸腺来源的基质成纤维细胞集落上形成的噬斑比骨髓来源的既多得多且本质上也更大。因此,在单层培养物中形成髓样噬斑的造血前体细胞与不同来源的基质机械细胞相互作用不同。

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