O'Leary D D, Stanfield B B, Cowan W M
Brain Res. 1981 Jul;227(4):607-17. doi: 10.1016/0165-3806(81)90012-2.
By using two fluorescent dyes that are retrogradely transported along axons, we have been able to demonstrate that many of the neurons in the parietal region of the rat cerebral cortex that can be labeled from the contralateral hemisphere early in postnatal development, persist well beyond the period when the callosal projection normally becomes restricted. This indicates that the major factor in the progressive restriction of the callosal projection is the withdrawal or degeneration of axon collaterals, rather than the selective death of many of the cells that initially project to the opposite side.
通过使用两种沿轴突逆行运输的荧光染料，我们已经能够证明，在出生后早期可从对侧半球标记的大鼠大脑皮质顶叶区域的许多神经元，在胼胝体投射通常开始受限的时期之后仍持续存在。这表明胼胝体投射逐渐受限的主要因素是轴突侧支的退缩或退化，而不是许多最初投射到对侧的细胞的选择性死亡。
