Lee D C, Lee M O, Kim C Y, Clifford D H
Can J Comp Med. 1981 Apr;45(2):182-7.
Ether, ethanol and aqueous extracts of ginseng were serially prepared from Korean ginseng plants. Each extract in the dose of 40 mg/kg was administered intravenously to ten dogs under light halothane anesthesia while 11 cardiovascular variables were compared during the ensuing two hours. The variable included cardiac output, stroke volume, heart rate, mean arterial pressure, pulse pressure, central venous pressure, total peripheral resistance, pH, PaCO2, PaO2 and base deficit. Following the administration of the ether extract (40 mg/kg) the heart rate and the central venous pressure decreased significantly. The administration of ethanol extract (40 mg/kg) caused a significant decrease in the heart rate and the mean arterial pressure. After the administration of the aqueous extract (40 mg/kg) the cardiac output, stroke volume and central venous pressure were significantly decreased, while the total peripheral resistance was significantly increased.
从高丽参植株中依次制备了人参的乙醚提取物、乙醇提取物和水提取物。在轻度氟烷麻醉下，将剂量为40毫克/千克的每种提取物静脉注射给10只狗，并在随后的两小时内比较11项心血管变量。这些变量包括心输出量、每搏输出量、心率、平均动脉压、脉压、中心静脉压、总外周阻力、pH值、动脉血二氧化碳分压、动脉血氧分压和碱缺失。给予乙醚提取物（40毫克/千克）后，心率和中心静脉压显著降低。给予乙醇提取物（40毫克/千克）导致心率和平均动脉压显著降低。给予水提取物（40毫克/千克）后，心输出量、每搏输出量和中心静脉压显著降低，而总外周阻力显著增加。
